The DECR1 Polyclonal Antibody (CAB13014) is a valuable tool for researchers studying DECR1, an essential enzyme involved in fatty acid metabolism and lipid biosynthesis. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for various research applications, including Western blot analysis. By binding to the DECR1 protein, this antibody enables precise detection and analysis in a variety of cell types, facilitating investigations in metabolism, lipid signaling, and energy regulation.
DECR1, also known as 2,4-dienoyl-CoA reductase, plays a crucial role in mitochondrial fatty acid beta-oxidation, which is essential for cellular energy production and lipid homeostasis. Dysregulation of DECR1 has been implicated in metabolic disorders, neurodegenerative diseases, and cancer, making it a promising target for therapeutic interventions. Understanding the function and regulation of DECR1 is vital for advancing research in metabolism-related pathologies and developing innovative treatment strategies.
Product Name:
DECR1 Rabbit Polyclonal Antibody
SKU:
CAB13014
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 35-335 of human DECR1 (NP_001350.1).
Enables 2,4-dienoyl-CoA reductase (NADPH) activity; NADPH binding activity; and identical protein binding activity. Involved in fatty acid beta-oxidation. Located in cytosol; mitochondrion; and nucleoplasm. Part of catalytic complex.
Purification Method:
Affinity purification
Gene ID:
1666
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DECR1 Rabbit pAb (CAB13014) at 1:2000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Negative control (NC): 293T.Exposuretime: 30s.
