The DDX6 Polyclonal Antibody (CAB16270) is a valuable tool for researchers studying DDX6, a protein known for its involvement in mRNA metabolism and translation regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications.DDX6, also referred to as RCK/p54, is a member of the DEAD-box RNA helicase family and plays a crucial role in post-transcriptional gene regulation. Its functions in mRNA decay and processing make it a key player in cellular processes such as RNA splicing, transport, and translation. By targeting DDX6 with this polyclonal antibody, researchers can accurately detect and analyze its expression levels in various cell types, providing valuable insights into its role in gene expression control.
The importance of DDX6 in gene expression and cellular function highlights its relevance in diverse fields of research, including molecular biology, developmental biology, and cancer biology. By using the DDX6 Polyclonal Antibody, researchers can further elucidate the mechanisms underlying mRNA regulation and potentially identify new therapeutic targets for diseases characterized by dysregulated gene expression.
Product Name:
DDX6 Rabbit Polyclonal Antibody
SKU:
CAB16270
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 384-483aa of human DDX6 (NP_001244120.1).
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
1656
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DDX6 Rabbit pAb (CAB16270) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
