RIG-I/DDX58 Rabbit Polyclonal Antibody (CAB13407)
- SKU:
- CAB13407
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | RIG-I/DDX58 Rabbit Polyclonal Antibody |
SKU: | CAB13407 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 726-925 of human Rig-I/DDX58 (NP_055129.2). |
Sequence: | QTRG RGRA RGSK CFLL TSNA GVIE KEQI NMYK EKMM NDSI LRLQ TWDE AVFR EKIL HIQT HEKF IRDS QEKP KPVP DKEN KKLL CRKC KALA CYTA DVRV IEEC HYTV LGDA FKEC FVSR PHPK PKQF SSFE KRAK IFCA RQNC SHDW GIHV KYKT FEIP VIKI ESFV VEDI ATGV QTLY SKWK DFHF EKIP FDPA EMSK |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | RIG1; DDX58; RIG-I; RLR-1; SGMRT2; Rig-I/DDX58 |
Positive Sample: | HepG2,Mouse brain,Mouse ovary,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell projection, Cytoplasm, cytoskeleton, ruffle membrane, tight junction. |
Calculated MW: | 107kDa |
Observed MW: | 102-110kDa |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.
Purification Method: | Affinity purification |
Gene ID: | 23586 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |