RIG-I/DDX58 Rabbit Polyclonal Antibody (CAB0550)
- SKU:
- CAB0550
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | RIG-I/DDX58 Rabbit Polyclonal Antibody |
SKU: | CAB0550 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 825-925 of human Rig-I/DDX58 (NP_055129.2). |
Sequence: | VIEE CHYT VLGD AFKE CFVS RPHP KPKQ FSSF EKRA KIFC ARQN CSHD WGIH VKYK TFEI PVIK IESF VVED IATG VQTL YSKW KDFH FEKI PFDP AEMS K |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:2000 - 1:4000 |
Synonyms: | RIG1; DDX58; RIG-I; RLR-1; SGMRT2; Rig-I/DDX58 |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell projection, Cytoplasm, cytoskeleton, ruffle membrane, tight junction. |
Calculated MW: | 107kDa |
Observed MW: | 107kDa |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.
Purification Method: | Affinity purification |
Gene ID: | 23586 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |