The DDX5 Polyclonal Antibody (CAB13294) is a valuable tool for researchers studying the DDX5 protein, a member of the DEAD box RNA helicase family involved in RNA metabolism and gene expression regulation. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications.DDX5, also known as p68, plays a crucial role in various cellular processes, including RNA splicing, transcription, and translation. Dysregulation of DDX5 has been implicated in cancer progression and other diseases, making it a promising target for therapeutic interventions.
The DDX5 Polyclonal Antibody enables precise detection and analysis of DDX5 expression in different cell types, providing valuable insights for studies in molecular biology, cancer research, and beyond.By enabling researchers to detect and analyze DDX5 protein levels, this antibody contributes to a deeper understanding of the functions and mechanisms of this important molecule. Its versatility and reliability make it an essential tool for investigating the roles of DDX5 in various biological processes, paving the way for advancements in both basic science and medicine.
Product Name:
DDX5 Rabbit Polyclonal Antibody
SKU:
CAB13294
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-614 of human DDX5 (NP_004387.1).
This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1655
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DDX5 Rabbit pAb (CAB13294) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
