DDX3Y Rabbit Polyclonal Antibody (CAB11704)
- SKU:
- CAB11704
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | DDX3Y Rabbit Polyclonal Antibody |
SKU: | CAB11704 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human DDX3Y (NP_001116137.1). |
Sequence: | MSHV VVKN DPEL DQQL ANLD LNSE KQSG GAST ASKG RYIP PHLR NREA SKGF HDKD SSGW SCSK DKDA YSSF GSRD SRGK PGYF SERG SGSR GRFD DRGR SDYD GIGN RERP GFGR FERS GHSR WCDK SVED DWSK PLPP SERL EQEL FSGG NTGI NFEK YDDI PVEA TGSN CPPH IENF SDID MGEI IMGN IELT RYTR PTPV QKHA IP |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | DBY; DDX3Y |
Positive Sample: | A-549,B cells,293T,A-431,HeLa,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 73kDa |
Observed MW: | 73kDa |
The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 8653 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |