The DDX3Y Polyclonal Antibody (CAB11704) is a valuable tool for researchers studying the DDX3Y protein, an essential component of RNA metabolism and viral replication. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the DDX3Y protein, this antibody enables the detection and analysis of DDX3Y in various cell types, making it ideal for studies in virology, cancer research, and RNA biology.
DDX3Y, a member of the DEAD-box RNA helicase family, is known for its role in RNA processing and translation regulation, making it a key player in viral infection and cancer development. Understanding the function and regulation of DDX3Y is crucial for developing targeted therapies for viral diseases and cancer. The DDX3Y Polyclonal Antibody offers researchers a reliable tool for investigating the intricate mechanisms involving DDX3Y and its potential as a therapeutic target.
Product Name:
DDX3Y Rabbit Polyclonal Antibody
SKU:
CAB11704
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human DDX3Y (NP_001116137.1).
The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
8653
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DDX3Y Rabbit pAb (CAB11704) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
