The DDX31 Polyclonal Antibody (CAB15892) is a valuable tool for researchers studying DDX31, a protein involved in RNA metabolism and regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the DDX31 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential component for studies in molecular biology and gene regulation.DDX31, a member of the DEAD box protein family, plays a crucial role in RNA processing and RNA-protein interactions.
Its functions in RNA splicing and translation make it a key player in gene expression and cellular processes. Research on DDX31 is particularly relevant in understanding diseases related to RNA dysfunction, such as cancer and developmental disorders. By studying the activity of DDX31, researchers can uncover novel insights into RNA biology and potential therapeutic targets for a range of diseases.
Product Name:
DDX31 Rabbit Polyclonal Antibody
SKU:
CAB15892
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 652-851 of human DDX31 (NP_073616.6).
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
64794
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from A-549 cells, using DDX31 Rabbit pAb (CAB15892) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
