DDX21 Rabbit Polyclonal Antibody (CAB7034)
- SKU:
- CAB7034
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | DDX21 Rabbit Polyclonal Antibody |
SKU: | CAB7034 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 624-783 of human DDX21 (NP_004719.2). |
Sequence: | VDQR SLIN SNVG FVTM ILQC SIEM PNIS YAWK ELKE QLGE EIDS KVKG MVFL KGKL GVCF DVPT ASVT EIQE KWHD SRRW QLSV ATEQ PELE GPRE GYGG FRGQ REGS RGFR GQRD GNRR FRGQ REGS RGPR GQRS GGGN KSNR SQNK GQKR SFSK AFGQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RH; GUA; GURDB; II/Gu; RH II/Gu; RH-II/GU; gu-alpha; RH-II/GuA; DDX21 |
Positive Sample: | SW620,MCF7,HepG2,293T,Mouse spleen,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, nucleolus, nucleoplasm. |
Calculated MW: | 87kDa |
Observed MW: | 100kDa |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
Purification Method: | Affinity purification |
Gene ID: | 9188 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |