DDX21 Rabbit Polyclonal Antibody (CAB14820)
- SKU:
- CAB14820
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | DDX21 Rabbit Polyclonal Antibody |
SKU: | CAB14820 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human DDX21 (NP_004719.2). |
Sequence: | MPGK LRSD AGLE SDTA MKKG ETLR KQTE EKEK KEKP KSDK TEEI AEEE ETVF PKAK QVKK KAEP SEVD MNSP KSKK AKKK EEPS QNDI SPKT KSLR KKKE PIEK KVVS SKTK KVTK NEEP SEEE IDAP KPKK MKKE KEMN GETR EKSP KLKN GFPH PEPD CNPS EAAS EESN SEIE QEIP |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | RH; GUA; GURDB; II/Gu; RH II/Gu; RH-II/GU; gu-alpha; RH-II/GuA; DDX21 |
Positive Sample: | HeLa,Jurkat,Hep G2,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, nucleolus, nucleoplasm. |
Calculated MW: | 87kDa |
Observed MW: | 100kDa |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
Purification Method: | Affinity purification |
Gene ID: | 9188 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |