The DDX21 Polyclonal Antibody (CAB14820) is a crucial tool for researchers studying DDX21, a key protein involved in RNA processing and gene regulation. This antibody, produced in rabbits, exhibits high sensitivity and specificity for human samples and has been validated for use in Western blot applications. By specifically binding to the DDX21 protein, this antibody enables precise detection and analysis in various cell types, making it an essential tool for investigations in molecular biology and cancer research.DDX21, also known as RNA helicase, plays a significant role in RNA metabolism and is essential for various cellular processes, including transcription and translation.
Its involvement in gene regulation and RNA processing makes it a promising target for studying diseases such as cancer and viral infections. By understanding the functions of DDX21, researchers can uncover new therapeutic strategies and potential drug targets for these conditions, advancing our knowledge and potential treatments in the field of molecular biology and oncology.
Product Name:
DDX21 Rabbit Polyclonal Antibody
SKU:
CAB14820
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human DDX21 (NP_004719.2).
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
Purification Method:
Affinity purification
Gene ID:
9188
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DDX21 Rabbit pAb (CAB14820) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
