The DDX20 Polyclonal Antibody (CAB5817) is a valuable tool for researchers studying the DDX20 protein, which is involved in RNA metabolism and RNA binding. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By targeting the DDX20 protein, this antibody enables the detection and analysis of DDX20 in various cell types, making it ideal for studies in molecular biology and gene expression research.DDX20, also known as RNA helicase DDX20, plays a crucial role in RNA processing and gene regulation, making it a key player in cellular functions such as transcription and translation.
Its involvement in RNA metabolism makes it a valuable target for research in fields such as developmental biology, cancer biology, and virology. Understanding the function of DDX20 can provide insights into various disease processes and may lead to the development of novel therapeutic strategies targeting RNA helicases.
Product Name:
DDX20 Rabbit Polyclonal Antibody
SKU:
CAB5817
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human DDX20 (NP_009135.4).
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs.
Purification Method:
Affinity purification
Gene ID:
11218
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DDX20 antibody (CAB5817) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
