DDX20 Rabbit Polyclonal Antibody (CAB5817)
- SKU:
- CAB5817
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | DDX20 Rabbit Polyclonal Antibody |
SKU: | CAB5817 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human DDX20 (NP_009135.4). |
Sequence: | VQVP APEP TPGP VRIL RTAQ DLSS PRTR TGDV LLAE PADF ESLL LSRP VLEG LRAA GFER PSPV QLKA IPLG RCGL DLIV QAKS GTGK TCVF STIA LDSL VLEN LSTQ ILIL APTR EIAV QIHS VITA IGIK MEGL ECHV FIGG TPLS QDKT RLKK CHIA VGSP GRIK QLIE LDYL NPGS IRLF ILDE ADKL LEEG SFQE QINW IYSS LPAS KQML AVSA TYPE FLAN ALTK YMRD PTFV RLNS SDPS LIGL KQYY |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:10 - 1:100 |
Synonyms: | DP103; GEMIN3; DDX20 |
Positive Sample: | MCF7,ES-2,293T,HepG2,HeLa,Mouse spleen,Rat testis,Mouse ovary |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, gem. |
Calculated MW: | 92kDa |
Observed MW: | 110kDa |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs.
Purification Method: | Affinity purification |
Gene ID: | 11218 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |