The DDX19A Polyclonal Antibody (PAC04250) is a valuable tool for researchers studying DDX19A, a key protein involved in RNA metabolism and processing. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the DDX19A protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and RNA biology.DDX19A, a member of the DEAD-box RNA helicase family, plays a crucial role in RNA splicing and transport processes, making it essential for gene expression regulation and mRNA maturation.
Its involvement in RNA metabolism suggests its potential as a target for research related to RNA-based diseases and disorders. Understanding the function of DDX19A is essential for advancing our knowledge of cellular processes and developing potential therapeutic interventions in conditions such as cancer, viral infections, and genetic disorders.
Western blot. All lanes: DDX19A antibody at 2µg/ml + Mouse gonad tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 54, 44 kDa. Observed band size: 54 kDa.
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO42250 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO42250 at dilution of 1:100.
Background:
ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19 functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins
