UniProt Protein Function: | DDX18: Probable RNA-dependent helicase. Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.Protein type: EC 3.6.4.13; Nucleolus; RNA-binding; HelicaseChromosomal Location of Human Ortholog: 2q14.1Cellular Component: membrane; nucleolusMolecular Function: protein binding; ATP binding; ATP-dependent RNA helicase activityBiological Process: metabolic process |
UniProt Protein Details: | |
NCBI Summary: | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NVP1 |
NCBI GenInfo Identifier: | 38327634 |
NCBI Gene ID: | 8886 |
NCBI Accession: | NP_006764.3 |
UniProt Secondary Accession: | Q9NVP1,Q6GTZ9, Q6IAU4, Q92732, Q9BQB7 |
UniProt Related Accession: | Q9NVP1 |
Molecular Weight: | 75,407 Da |
NCBI Full Name: | ATP-dependent RNA helicase DDX18 |
NCBI Synonym Full Names: | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 |
NCBI Official Symbol: | DDX18Â Â |
NCBI Official Synonym Symbols: | MrDb  |
NCBI Protein Information: | ATP-dependent RNA helicase DDX18; DEAD box protein 18; Myc-regulated DEAD box protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 18 (Myc-regulated) |
UniProt Protein Name: | ATP-dependent RNA helicase DDX18 |
UniProt Synonym Protein Names: | DEAD box protein 18; Myc-regulated DEAD box protein; MrDb |
Protein Family: | ATP-dependent RNA helicase |
UniProt Gene Name: | DDX18Â Â |
UniProt Entry Name: | DDX18_HUMAN |