Based on the information on the provided URL, we have the following product description:The DDX17 Rabbit Monoclonal Antibody (CAB5731) is a valuable tool for research involving DDX17, a protein known for its involvement in RNA processing and gene regulation. This antibody, produced using rabbit monoclonal technology, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.DDX17, also known as RNA helicase A, plays a crucial role in RNA metabolism by unwinding RNA structures and facilitating various RNA-related processes, such as splicing and translation.
Its importance in gene expression regulation makes it a key target for studies in molecular biology and cancer research.Understanding the function of DDX17 can provide insights into its role in cellular processes and its potential implications in disease states. By using the DDX17 Rabbit Monoclonal Antibody, researchers can effectively detect and analyze DDX17 expression in different cell types, contributing to a better understanding of its functions and its potential as a therapeutic target in various diseases.
Product Name:
DDX17 Rabbit Monoclonal Antibody
SKU:
CAB5731
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human DDX17 (Q92841).
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon.
Purification Method:
Affinity purification
Gene ID:
10521
Clone Number:
ARC1413
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DDX17 Rabbit mAb (CAB5731) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
