DDX11 Rabbit Polyclonal Antibody (CAB7666)
- SKU:
- CAB7666
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | DDX11 Rabbit Polyclonal Antibody |
SKU: | CAB7666 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DDX11 (NP_689651.1). |
Sequence: | MANE TQKV GAIH FPFP FTPY SIQE DFMA ELYR VLEA GKIG IFES PTGT GKSL SLIC GALS WLRD FEQK KREE EARL LETG TGPL HDEK DESL CLSS SCEG AAGT PRPA GEPA WVTQ FVQK KEER DLVD RLKA EQAR RKQR EERL QQLQ HRVQ LKYA AKRL RQEE EERE NLLR LSRE MLET GPEA ERLE QLES GEEE LVLA EYES DEEK KVAS RVDE DEDD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CHL1; KRG2; WABS; CHLR1; DDX11 |
Positive Sample: | HT-29,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, nucleolus. |
Calculated MW: | 108kDa |
Observed MW: | 108kDa |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 1663 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |