The DDR2 Rabbit Monoclonal Antibody (CAB4296) is a valuable tool for researchers studying DDR2, a cell surface receptor involved in cell adhesion and migration. This antibody, generated using rabbit monoclonal technology, is highly specific to DDR2 and is suitable for use in various applications such as Western blot and immunohistochemistry.DDR2, a member of the discoidin domain receptor family, plays a crucial role in cell signaling processes related to extracellular matrix remodeling and tissue repair. Dysregulation of DDR2 expression has been implicated in various diseases, including cancer and fibrosis.
By targeting DDR2 with this antibody, researchers can gain insight into its function and role in disease pathology.With its high specificity and sensitivity, the DDR2 Rabbit Monoclonal Antibody (CAB4296) is an essential tool for investigating the molecular mechanisms underlying DDR2 signaling pathways. Its versatility and reliability make it a valuable asset for studies in cancer biology, tissue remodeling, and drug development aiming to target DDR2 for therapeutic purposes.
Product Name:
DDR2 Rabbit Monoclonal Antibody
SKU:
CAB4296
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 756-855 of human DDR2 (Q16832).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
97kDa
Observed MW:
110kDa
This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia.
Purification Method:
Affinity purification
Gene ID:
4921
Clone Number:
ARC0958
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DDR2 Rabbit mAb (CAB4296) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
