DDR1/MCK10/CD167a Monoclonal Antibody (CAB22705)
- SKU:
- CAB22705
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | DDR1/MCK10/CD167a Monoclonal Antibody |
| SKU: | CAB22705 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Mouse |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-416 of human DDR1/MCK10/CD167a(NP_054699.2). |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:500 - 1:1000 |
| Synonyms: | CAK; DDR; NEP; HGK2; PTK3; RTK6; TRKE; CD167; EDDR1; MCK10; NTRK4; PTK3A; DDR1/MCK10/CD167a |
| Positive Sample: | Mouse brain |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein. |
| Calculated MW: | 101kDa |
| Observed MW: | 125kDa |
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
| Purification Method: | Affinity purification |
| Gene ID: | 780 |
| Clone Number: | ARC58637 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |
 | Western blot analysis of Mouse brain, using DDR1/MCK10/CD167a antibody (CAB22705) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s. |
Related Products
Human MCK10 / DDR1 ELISA Kit
Anti-DDR1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0306)
DDR1 Rabbit Polyclonal Antibody (CAB10487)
