DDC Rabbit Polyclonal Antibody (CAB3828)
- SKU:
- CAB3828
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | DDC Rabbit Polyclonal Antibody |
SKU: | CAB3828 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human DDC (NP_000781.2). |
Sequence: | MNAS EFRR RGKE MVDY MANY MEGI EGRQ VYPD VEPG YLRP LIPA AAPQ EPDT FEDI INDV EKII MPGV THWH SPYF FAYF PTAS SYPA MLAD MLCG AIGC IGFS WAAS PACT ELET VMMD WLGK MLEL PKAF LNEK A |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | AADC; DDC |
Positive Sample: | SH-SY5Y,Mouse liver,Mouse brain,Mouse kidney,Rat liver,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | axon, cytoplasm, cytosol, extracellular exosome, synaptic vesicle |
Calculated MW: | 54kDa |
Observed MW: | 37kDa/54kDa |
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1644 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |