The DDAH2 Rabbit Monoclonal Antibody (CAB4159) is a valuable tool for researchers studying dimethylarginine dimethylaminohydrolase 2 (DDAH2), an enzyme involved in nitric oxide metabolism and cardiovascular health. This highly specific antibody, developed using rabbit monoclonal technology, is suitable for use in various experimental applications, including Western blotting, immunohistochemistry, and immunofluorescence.DDAH2 plays a crucial role in regulating nitric oxide levels in the body, impacting vascular function, blood pressure regulation, and cardiovascular health. Dysregulation of DDAH2 activity has been implicated in various cardiovascular diseases, making it an attractive target for therapeutic intervention.
By utilizing the DDAH2 Rabbit Monoclonal Antibody (CAB4159), researchers can accurately detect and measure DDAH2 expression levels in different cell types and tissues, advancing our understanding of its physiological and pathological roles.In conclusion, the DDAH2 Rabbit Monoclonal Antibody (CAB4159) offers reliable and specific detection of DDAH2 protein, making it an essential tool for scientists studying nitric oxide signaling, cardiovascular diseases, and potential therapeutic strategies targeting DDAH2 function.
Product Name:
DDAH2 Rabbit Monoclonal Antibody
SKU:
CAB4159
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DDAH2 (O95865).
This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23564
Clone Number:
ARC0910
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DDAH2 Rabbit mAb (CAB4159) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.