The DCUN1D1 Polyclonal Antibody (CAB14587) is a valuable tool for research involving DCUN1D1, a key protein involved in neddylation, a process that regulates protein degradation and cell cycle progression. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the DCUN1D1 protein, researchers can detect and analyze its expression in various cell types, making it an ideal choice for studies in cancer biology and cell cycle regulation.DCUN1D1, also known as DCN1-like protein 1, is essential for neddylation, a post-translational modification process that plays a crucial role in the regulation of protein stability and function.
Dysregulation of DCUN1D1 has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions. Research into the role of DCUN1D1 in protein degradation pathways is vital for developing targeted therapies that can modulate protein turnover and potentially treat diseases associated with aberrant protein degradation.
Product Name:
DCUN1D1 Rabbit Polyclonal Antibody
SKU:
CAB14587
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 15-70 of human DCUN1D1 (NP_065691.2).
Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation and regulation of protein ubiquitination. Located in cytosol and nucleoplasm. Part of ubiquitin ligase complex.
Purification Method:
Affinity purification
Gene ID:
54165
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DCUN1D1 Rabbit pAb (CAB14587) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
