The DCTN5 Polyclonal Antibody (CAB15915) is a valuable tool for research involving Dynactin-5 (DCTN5), a protein associated with the dynactin complex that is involved in intracellular transport and cargo binding. The antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the DCTN5 protein, this antibody enables the detection and analysis of DCTN5 in various cell types, making it an ideal choice for studies in cell biology and molecular transport mechanisms.DCTN5 is a crucial component of the dynactin complex, which is essential for the proper functioning of molecular motors involved in intracellular transport processes. Dysregulation of DCTN5 has been implicated in various diseases, including neurodegenerative disorders and certain types of cancer.
By studying the role of DCTN5 in cellular transport pathways, researchers can gain valuable insights into disease mechanisms and identify potential therapeutic targets for intervention.Overall, the DCTN5 Polyclonal Antibody (CAB15915) is a reliable tool for investigating the function and regulation of DCTN5 in cellular processes, with implications for a wide range of research areas including neuroscience, oncology, and molecular biology. Its specificity and sensitivity make it a valuable asset for scientists seeking to deepen their understanding of intracellular transport dynamics and their impact on human health.
Product Name:
DCTN5 Rabbit Polyclonal Antibody
SKU:
CAB15915
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DCTN5 (NP_115875.1).
This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
84516
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DCTN5 Rabbit pAb (CAB15915) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
