The DCTD Polyclonal Antibody (CAB5889) is a valuable tool for research involving DCTD, a key enzyme involved in DNA synthesis and repair. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting. By binding to the DCTD protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.DCTD, also known as deoxycytidylate deaminase, plays a crucial role in maintaining genomic stability and integrity by ensuring accurate nucleotide incorporation during DNA replication.
Dysregulation of DCTD activity has been implicated in various diseases, including cancer and genetic disorders. Therefore, investigating the function of DCTD is essential for understanding its role in these pathologies and developing targeted therapies.Overall, the DCTD Polyclonal Antibody (CAB5889) is a valuable tool for researchers interested in studying the molecular mechanisms underlying DNA synthesis and repair, as well as exploring the potential therapeutic implications of targeting DCTD in disease contexts.
Product Name:
DCTD Rabbit Polyclonal Antibody
SKU:
CAB5889
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-178 of human DCTD (NP_001912.2).
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1635
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DCTD Rabbit pAb (CAB5889) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
