The DCSTAMP Polyclonal Antibody (CAB14630) is specifically designed for researchers studying DCSTAMP, a key cell surface protein involved in osteoclast differentiation and function. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the DCSTAMP protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in bone biology and related fields.DCSTAMP plays a critical role in osteoclast fusion and multinucleation, processes that are essential for bone resorption and remodeling.
Dysregulation of DCSTAMP activity has been implicated in various bone disorders, including osteoporosis and osteopetrosis, making it an attractive target for research aimed at understanding and treating these conditions. By elucidating the mechanisms underlying DCSTAMP function, researchers can pave the way for the development of novel therapeutic approaches for bone diseases.
Product Name:
DCSTAMP Rabbit Polyclonal Antibody
SKU:
CAB14630
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 401-470 of human DCSTAMP (NP_110415.1).
This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
81501
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using DCSTAMP Rabbit pAb (CAB14630) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
