DcR1 / CD263 Monoclonal Antibody (CAB23554)
- SKU:
- CAB23554
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | DcR1 / CD263 Monoclonal Antibody |
SKU: | CAB23554 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-230 of human DcR1 / CD263 (NP_003832.2). |
Sequence: | VEEF GANA TVET PAAE ETMN TSPG TPAP AAEE TMNT SPGT PAPA AEET MTTS PGTP APAA EETM TTSP GTPA PAAE ETMI T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR; DcR1 / CD263 |
Positive Sample: | Jurkat,Raji,A20,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Lipid-anchor. |
Calculated MW: | 27kDa |
Observed MW: | 28kDa |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
Purification Method: | Affinity purification |
Gene ID: | 8794 |
Clone Number: | ARC3107 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |