The DCR1/CD263 Monoclonal Antibody is a cutting-edge tool for research in the field of immunology and cancer studies. This antibody specifically targets the CD263 protein, which is involved in immune regulation and inhibiting immune responses. Produced using advanced techniques, this monoclonal antibody offers high specificity and sensitivity in detecting and analyzing CD263 in various cell types. It is validated for use in Western blot applications and has been shown to be highly reactive with human samples.CD263, also known as a key immune regulatory molecule, plays a crucial role in maintaining immune homeostasis by controlling inflammation and allergen responses.
Research on CD263 has great potential in advancing our understanding of diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.By using the DCR1/CD263 Monoclonal Antibody, researchers can gain valuable insights into the function of CD263 and its role in immune modulation. This antibody is an essential tool for studies aiming to develop innovative therapies targeting immune responses in various disease contexts.
Product Name:
DcR1 / CD263 Monoclonal Antibody
SKU:
CAB23554
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-230 of human DcR1 / CD263 (NP_003832.2).
Sequence:
VEEF GANA TVET PAAE ETMN TSPG TPAP AAEE TMNT SPGT PAPA AEET MTTS PGTP APAA EETM TTSP GTPA PAAE ETMI T
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
Purification Method:
Affinity purification
Gene ID:
8794
Clone Number:
ARC3107
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using DcR1 / CD263 Rabbit mAb (CAB23554) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
