DCPS Rabbit Polyclonal Antibody (CAB10299)
- SKU:
- CAB10299
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | DCPS Rabbit Polyclonal Antibody |
SKU: | CAB10299 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human DCPS (NP_054745.1). |
Sequence: | MADA APQL GKRK RELD VEEA HAAS TEEK EAGV GNGT CAPV RLPF SGFR LQKV LRES ARDK IIFL HGKV NEAS GDGD GEDA VVIL EKTP FQVE QVAQ LLTG SPEL QLQF SNDI YSTY HLFP PRQL NDVK TTVV YPAT EKHL QKYL RQDL RLIR ETGD DYRN ITLP HLES QSLS IQWV YNIL DKKA EADR IVFE NPDP SDGF VLIP DLKW NQQQ LDDL YLIA ICHR RGIR SLRD LTPE HLPL LRNI LHQG QEAI LQRY RMKG DHLR VYLH YL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | ARS; DCS1; HSL1; HINT5; HINT-5; HSPC015; DCPS |
Positive Sample: | HT-29 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 39kDa |
Observed MW: | 38kDa |
This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover.
Purification Method: | Affinity purification |
Gene ID: | 28960 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |