The DCPS Polyclonal Antibody (CAB10299) is a valuable tool for researchers studying DCPS, a key enzyme involved in RNA metabolism and mRNA decapping. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting. It specifically binds to the DCPS protein, enabling precise detection and analysis in different cell types.DCPS, or diphosphatase, plays a crucial role in RNA degradation and gene expression regulation. Dysfunction of this enzyme has been linked to various diseases, including cancer and neurological disorders.
By targeting DCPS, researchers can gain insights into the mechanisms underlying these conditions and potentially develop novel therapeutic approaches.The DCPS Polyclonal Antibody is a valuable tool for investigating the function and regulation of DCPS in health and disease. Its high specificity and sensitivity make it an excellent choice for studies in molecular biology, oncology, and neurology, providing researchers with a powerful resource for advancing their research objectives.
Product Name:
DCPS Rabbit Polyclonal Antibody
SKU:
CAB10299
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human DCPS (NP_054745.1).
This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover.
Purification Method:
Affinity purification
Gene ID:
28960
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HT-29 cells, using DCPS Rabbit pAb (CAB10299) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
