The DCP2 Polyclonal Antibody (CAB8282) offered by Assay Genie is a valuable tool for research involving DCP2, a protein involved in RNA degradation processes. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. It binds specifically to the DCP2 protein, allowing for accurate detection and analysis in a variety of cell types.DCP2 is a key player in mRNA decapping, a critical step in the regulation of gene expression and RNA turnover. Dysregulation of DCP2 has been implicated in various disease processes, making it an important target for research in areas such as cancer, neurodegenerative disorders, and viral infections.
Understanding the function and regulation of DCP2 is essential for gaining insights into these disease mechanisms and identifying potential therapeutic targets.By using the DCP2 Polyclonal Antibody (CAB8282), researchers can further explore the role of DCP2 in cellular processes and disease pathways, ultimately advancing our understanding of RNA biology and potential treatment strategies.
Product Name:
DCP2 Rabbit Polyclonal Antibody
SKU:
CAB8282
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human DCP2 (NP_001229306.1).
The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
167227
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using DCP2 Rabbit pAb (CAB8282) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
