The DCP1A Rabbit Monoclonal Antibody (CAB6824) is a valuable tool for researchers studying DCP1A, a key protein involved in mRNA decapping and decay processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications. By binding specifically to the DCP1A protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for investigations in RNA biology and gene expression regulation.DCP1A is essential for mRNA degradation and turnover, playing a crucial role in maintaining cellular homeostasis and gene expression control.
Dysregulation of DCP1A has been implicated in diseases such as cancer, neurodegenerative disorders, and viral infections, highlighting its significance in various pathological conditions. Understanding the function and regulation of DCP1A is vital for developing targeted therapies and interventions aimed at modulating mRNA decay processes in disease contexts.
Product Name:
DCP1A Rabbit Monoclonal Antibody
SKU:
CAB6824
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 483-582 of human DCP1A (Q9NPI6).
Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55802
Clone Number:
ARC1421
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using DCP1A Rabbit mAb (CAB6824) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
