The DCP1A Polyclonal Antibody (CAB7376) is a valuable tool for researchers studying DCP1A, a key player in mRNA decapping and degradation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to DCP1A protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and RNA metabolism.DCP1A is a critical component of the mRNA degradation pathway, playing a crucial role in post-transcriptional gene regulation. Its involvement in mRNA processing has implications for the control of gene expression and cellular responses to environmental stimuli.
Research on DCP1A is essential for advancing our understanding of gene regulation mechanisms and the development of therapeutic strategies targeting RNA degradation pathways.Overall, the DCP1A Polyclonal Antibody is a versatile tool for researchers exploring the intricate processes of mRNA decay and the regulation of gene expression. Its ability to specifically target DCP1A protein in various experimental settings makes it a valuable asset in the fields of molecular biology, biochemistry, and gene regulation studies.
Product Name:
DCP1A Rabbit Polyclonal Antibody
SKU:
CAB7376
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 303-582 of human DCP1A (NP_060873.4).
Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55802
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DCP1A Rabbit pAb (CAB7376) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
