DCLRE1C Polyclonal Antibody (CAB5615)
- SKU:
- CAB5615
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DCLRE1C Polyclonal Antibody |
SKU: | CAB5615 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DCLRE1C (NP_001029027.1). |
Sequence: | MSSF EGQM AEYP TISI DRFD RENL RARA YFLS HCHK DHMK GLRA PTLK RRLE CSLK VYLY CSPV TKEL LLTS PKYR FWKK RIIS IEIE TPTQ ISLV DEAS GEKE EIVV TLLP AGHC PGSV MFLF QGNN GTVL YTGD FRLA QGEA ARME LLHS GGRV KDIQ SVYL DTTF CDPR FYQI PSRE ECLS GVLE LVRS WITR SPYH VVWL NCKA AYGY EYLF TNLS EELG VQVH VNKL DMFR NMPE ILHH LTTD RNTQ IHAC RHPK AEEY FQWS KLPC GITS RNRI PLHI ISIK PSTM WFGE RSRK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SCIDA; SNM1C; A-SCID; RS-SCID; DCLREC1C; DCLRE1C |
Positive Sample: | Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 78kDa |
Observed MW: | 90kDa |
This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 64421 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |