The DCDC2 Polyclonal Antibody (CAB17704) is a valuable tool for researchers studying the DCDC2 protein, which plays a crucial role in brain development and function. This antibody, derived from rabbit polyclonal sources, is highly specific to human samples and is suitable for use in Western blot applications. By targeting the DCDC2 protein, researchers can effectively detect and analyze its expression in various cell types, making it an ideal choice for studies focused on neuroscience and neurodevelopmental disorders.
DCDC2 is a key player in the development of neural circuits and plays a role in processes such as neuronal migration and axon guidance. Dysregulation of DCDC2 has been linked to conditions such as dyslexia and developmental language disorders, highlighting its importance in neurobiology research. By understanding the function of DCDC2, researchers may uncover new insights into neurological disorders and potentially develop targeted therapies to address these conditions.
Product Name:
DCDC2 Rabbit Polyclonal Antibody
SKU:
CAB17704
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human DCDC2 (NP_001182539).
This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
51473
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DCDC2 Rabbit pAb (CAB17704) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
