The DCAF7 Polyclonal Antibody (CAB13392) is a vital tool for researchers studying DCAF7, a protein involved in protein degradation pathways and cell cycle regulation. This antibody, generated in rabbits, exhibits high specificity for human samples and is validated for use in immunohistochemistry and Western blotting.DCAF7, also known as VPRBP, is a substrate recognition component of the E3 ubiquitin ligase complex and plays a crucial role in the targeted degradation of specific proteins. Its involvement in cell cycle progression and DNA damage response makes it an interesting target for studies on cancer biology, cell signaling, and genotoxic stress.
By utilizing the DCAF7 Polyclonal Antibody, researchers can effectively detect and analyze the expression of DCAF7 in various cell types, providing valuable insights into its function and potential therapeutic applications. This antibody is a valuable tool for furthering our understanding of protein degradation pathways and their impact on cellular processes.
Product Name:
DCAF7 Rabbit Polyclonal Antibody
SKU:
CAB13392
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human DCAF7 (NP_005819.3).
This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10238
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of U2OS cells using DCAF7 antibody (CAB13392). Blue: DAPI for nuclear staining.
