The DCAF17 Polyclonal Antibody (CAB17776) is a valuable tool for researchers studying DCAF17, a protein involved in cell cycle regulation and protein degradation pathways. This rabbit polyclonal antibody is highly specific to human samples and is suitable for use in Western blot applications. By binding to the DCAF17 protein, this antibody enables the detection and analysis of DCAF17 in various cell types, making it an essential tool for studying cell cycle regulation and protein degradation mechanisms.DCAF17, also known as DDB1- and CUL4-associated factor 17, plays a crucial role in targeting specific substrates for degradation through the CUL4-DDB1 E3 ubiquitin ligase complex.
Dysregulation of DCAF17 has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions. Understanding the function of DCAF17 is essential for unraveling its role in disease development and progression, and the DCAF17 Polyclonal Antibody (CAB17776) provides researchers with a reliable tool for these investigations.
Product Name:
DCAF17 Rabbit Polyclonal Antibody
SKU:
CAB17776
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 235-335 of human DCAF17 (NP_079276.2).
This gene encodes a nuclear transmembrane protein that associates with cullin 4A/damaged DNA binding protein 1 ubiquitin ligase complex. Mutations in this gene are associated with Woodhouse-Sakati syndrome. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
80067
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DCAF17 Rabbit pAb (CAB17776) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
