The DCAF13 Polyclonal Antibody (CAB13213) is specifically designed for research involving DCAF13, a protein involved in the regulation of protein degradation and cell cycle control. This antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It targets the DCAF13 protein, allowing for detection and analysis in various cell types, making it a valuable tool for studying cell biology and cancer research.DCAF13 is a key player in the ubiquitin-proteasome system, which is responsible for degrading damaged or unwanted proteins within cells.
Dysregulation of this system has been linked to various diseases, including cancer and neurodegenerative disorders. By understanding the function of DCAF13, researchers can gain insights into the mechanisms of protein degradation and potentially develop new therapeutic strategies for treating these diseases.Overall, the DCAF13 Polyclonal Antibody provides researchers with a reliable tool for investigating the role of DCAF13 in cellular processes and disease pathology, offering new opportunities for advancing our understanding of protein regulation and potential therapeutic interventions.
Product Name:
DCAF13 Rabbit Polyclonal Antibody
SKU:
CAB13213
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human DCAF13 (NP_056235.4).
Enables estrogen receptor binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in several cellular components, including centrosome; cytosol; and nuclear lumen. Part of Cul4-RING E3 ubiquitin ligase complex.
Purification Method:
Affinity purification
Gene ID:
25879
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DCAF13 Rabbit pAb (CAB13213) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
