The DCAF12 Polyclonal Antibody (CAB16510) is a valuable tool for researchers studying DCAF12, a protein involved in various cellular processes. This antibody, produced in rabbits, is highly specific to human samples and is recommended for use in Western blot applications. By binding to the DCAF12 protein, this antibody allows for precise detection and analysis in different cell types, making it an excellent choice for studies in molecular biology and cell biology.DCAF12, also known as DDB1- and CUL4-associated factor 12, plays a crucial role in the regulation of protein degradation and cell cycle progression.
Its involvement in these essential cellular functions makes it a compelling target for research into diseases like cancer, neurodegenerative disorders, and developmental abnormalities. Understanding the mechanisms by which DCAF12 operates is key to developing targeted therapies that could potentially treat or prevent these conditions.
Product Name:
DCAF12 Rabbit Polyclonal Antibody
SKU:
CAB16510
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human DCAF12 (NP_056212.1).
This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates.
Purification Method:
Affinity purification
Gene ID:
25853
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DCAF12 Rabbit pAb (CAB16510) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
