The DBP Polyclonal Antibody (CAB15270) is a valuable tool for researchers studying the vitamin D-binding protein (DBP), a key player in the transport and metabolism of vitamin D in the body. This antibody, raised in rabbits, displays high reactivity with human samples and has been validated for use in Western blot applications.DBP is essential for the transport of vitamin D metabolites in the bloodstream, where it plays a crucial role in regulating the bioavailability and activation of vitamin D. Research has shown that DBP levels are associated with various health conditions, including cancer, osteoporosis, and chronic kidney disease.
Understanding the function and regulation of DBP is important for unraveling its role in disease pathology and developing potential diagnostic or therapeutic strategies.The DBP Polyclonal Antibody enables specific detection and analysis of DBP protein levels in various cell types and tissues, making it an invaluable tool for studies in metabolism, endocrinology, and disease research. By targeting DBP, researchers can gain insights into the mechanisms underlying vitamin D metabolism and its implications for health and disease.
Product Name:
DBP Rabbit Polyclonal Antibody
SKU:
CAB15270
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human DBP (NP_001343.2).
The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes.
Purification Method:
Affinity purification
Gene ID:
1628
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of SK-BR-3, using DBP Rabbit pAb (CAB15270) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
