DBN1 Rabbit Polyclonal Antibody (CAB6366)
- SKU:
- CAB6366
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | DBN1 Rabbit Polyclonal Antibody |
SKU: | CAB6366 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-649 of human DBN1 (NP_004386.2). |
Sequence: | EQIE RALD EVTS SQPP PLPP PPPP AQET QEPS PILD SEET RAAA PQAW AGPM EEPP QAQA PPRG PGSP AEDL MFME SAEQ AVLA APVE PATA DATE IHDA ADTI ETDT ATAD TTVA NNVP PAAT SLID LWPG NGEG ASTL QGEP RAPT PPSG TEVT LAEV PLLD EVAP EPLL PAGE GCAT LLNF DELP EPPA TFCD PEEV EGEP LAAP QTPT LPSA LEEL EQEQ EPEP HLLT NGET TQKE GTQA SEGY FSQS QEEE FAQS EELC AKAP PPVF YNKP PEID ITCW DADP VPEE EEGF EGGD |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | D0S117E; DBN1 |
Positive Sample: | BT-474,HeLa,SKOV3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell projection, Cytoplasm, cell cortex, growth cone. |
Calculated MW: | 71kDa |
Observed MW: | 110kDa |
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1627 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |