DAZ2 Rabbit Polyclonal Antibody (CAB7600)
- SKU:
- CAB7600
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
Product Name: | DAZ2 Rabbit Polyclonal Antibody |
SKU: | CAB7600 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DAZ2 (NP_001005785.1). |
Sequence: | MSAA NPET PNST ISRE ASTQ SSSA AASQ GWVL PEGK IVPN TVFV GGID ARMD ETEI GSCF GRYG SVKE VKII TNRT GVSK GYGF VSFV NDVD VQKI VGSQ IHFH GKKL KLGP AIRK QKLC ARHV QPRP LVVN PPPP PQFQ NVWR NPNT ETYL QPQI TPNP VTQH VQAY SAYP HSPG QVIT GCQL LVYN YQEY PTYP DSAF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | pDP1678; DAZ2 |
Positive Sample: | Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 63kDa |
Observed MW: | 63kDa |
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 57055 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |