The DARS2 Polyclonal Antibody (CAB7813) is a highly specific research tool designed for the detection and analysis of DARS2 protein. DARS2 is an important enzyme involved in mitochondrial function and is linked to various diseases, including leukoencephalopathy and hypertrophic cardiomyopathy. The antibody, produced in rabbits, is suitable for use in Western blot applications and is highly reactive with human samples.
Its ability to bind specifically to the DARS2 protein enables researchers to study its role in mitochondrial biology and disease pathology. This antibody is a valuable resource for studies in molecular biology, genetics, and neurology, providing insights into the mechanisms underlying mitochondrial dysfunction and its implications for human health.
Product Name:
DARS2 Rabbit Polyclonal Antibody
SKU:
CAB7813
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 406-645 of human DARS2 (NP_060592.2).
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).
Purification Method:
Affinity purification
Gene ID:
55157
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DARS2 Rabbit pAb (CAB7813) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
