The Dapper Homolog 3 Polyclonal Antibody (CAB8280) is a valuable tool for research involving Dapper Homolog 3 (DACT3), a protein known for its role in various cellular processes such as cell proliferation and differentiation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot and immunohistochemistry applications.DACT3 is a key player in the Wnt signaling pathway, which is essential for embryonic development and tissue homeostasis. Dysregulation of this pathway has been linked to various diseases, including cancer and developmental disorders.
By detecting DACT3 expression in different cell types, this antibody allows for insightful analysis in developmental biology and cancer research studies.Furthermore, the Dapper Homolog 3 Polyclonal Antibody is an important tool for investigating the molecular mechanisms underlying Wnt signaling and its implications in disease progression. Its high reactivity and specificity make it an ideal choice for researchers looking to explore the role of DACT3 in cellular processes and pathogenesis.
Product Name:
DACT3 Rabbit Polyclonal Antibody
SKU:
CAB8280
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human DACT3 (NP_659493.2).
Predicted to enable delta-catenin binding activity; protein kinase A binding activity; and protein kinase C binding activity. Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of cell growth. Predicted to be active in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
147906
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using DACT3 Rabbit pAb (CAB8280) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
