The DAPK1 Polyclonal Antibody (CAB5741) is a valuable tool for researchers studying the protein DAPK1, a key regulator of cell death and apoptosis. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to DAPK1, this antibody enables the detection and analysis of this important protein in a variety of cell types.DAPK1, also known as Death-associated protein kinase 1, is involved in a variety of cellular processes, including apoptosis, autophagy, and immune response regulation.
Dysregulation of DAPK1 has been linked to various diseases, such as cancer, neurodegenerative disorders, and autoimmune conditions. Understanding the function of DAPK1 is crucial for developing targeted therapies for these diseases.Researchers in the fields of cancer biology, neurology, and immunology will find the DAPK1 Polyclonal Antibody to be a valuable asset in their studies. Its high specificity and sensitivity make it an ideal tool for investigating the role of DAPK1 in health and disease.
Product Name:
DAP Kinase 1 (DAPK1) Rabbit Polyclonal Antibody
SKU:
CAB5741
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1141-1430 of human DAP Kinase 1 (DAPK1) (NP_004929.2).
Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1612
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DAP Kinase 1 (DAP Kinase 1 (DAPK1)) Antibody (CAB5741) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
