DAP3 Rabbit Polyclonal Antibody (CAB7003)
- SKU:
- CAB7003
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
Product Name: | DAP3 Rabbit Polyclonal Antibody |
SKU: | CAB7003 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 159-398 of human DAP3 (NP_387506.1). |
Sequence: | HLWV KNCR DLLQ SSYN KQRF DQPL EAST WLKN FKTT NERF LNQI KVQE KYVW NKRE STEK GSPL GEVV EQGI TRVR NATD AVGI VLKE LKRQ SSLG MFHL LVAV DGIN ALWG RTTL KRED KSPI APEE LALV HNLR KMMK NDWH GGAI VSAL SQTG SLFK PRKA YLPQ ELLG KEGF DALD PFIP ILVS NYNP KEFE SCIQ YYLE NNWL QHEK APTE EGKK ELLF LSNA NPSL LERH CAYL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DAP-3; S29mt; MRPS29; MRP-S29; bMRP-10; DAP3 |
Positive Sample: | MCF7,Jurkat,Mouse kidney,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 46kDa |
Observed MW: | 46kDa |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.
Purification Method: | Affinity purification |
Gene ID: | 7818 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |