The DAP Kinase 1 Rabbit Monoclonal Antibody is a valuable tool for researchers studying DAP Kinase 1, an important regulator of apoptosis and tumor suppression. This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting DAP Kinase 1 in various experimental settings, including Western blot applications.DAP Kinase 1, a pro-apoptotic protein, is known for its role in promoting programmed cell death and inhibiting tumor growth. Dysregulation of DAP Kinase 1 has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions.
By using this antibody, researchers can gain insights into the function and regulation of DAP Kinase 1 in different biological contexts, advancing our understanding of its potential implications in cancer biology and other disorders.Overall, the DAP Kinase 1 Rabbit Monoclonal Antibody offers a powerful tool for investigating the molecular mechanisms underlying apoptosis and cancer development, ultimately contributing to the development of innovative therapeutic strategies targeting DAP Kinase 1.
Product Name:
DAP Kinase 1 (DAPK1) Rabbit Monoclonal Antibody
SKU:
CAB11459
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human DAP Kinase 1 (DAPK1) (P53355).
Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1612
Clone Number:
ARC0601
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DAP Kinase 1 (DAPK1) Rabbit mAb (CAB11459) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.