The DALRD3 Antibody (PAC036258) is a highly specific and sensitive tool for researchers studying DALRD3, a critical protein involved in DNA damage and repair processes. This antibody, produced in rabbits, has been validated for use in multiple applications, including Western blot and immunohistochemistry assays. By binding to DALRD3, researchers can accurately detect and analyze the expression of this protein in various cell types, providing valuable insights into its role in genotoxic stress response.DALRD3, also known as DNA ligase 3, is essential for maintaining genomic stability and integrity by repairing DNA breaks and lesions.
Dysregulation of DALRD3 has been implicated in various diseases, including cancer and genetic disorders. Studying the function of DALRD3 is crucial for understanding how cells respond to DNA damage and for developing targeted therapies to treat diseases associated with genomic instability.Overall, the DALRD3 Antibody (PAC036258) is a valuable tool for researchers interested in unraveling the molecular mechanisms underlying DNA repair processes and their implications for human health and disease. Its high specificity and sensitivity make it an essential reagent for studies in molecular biology, cancer research, and genomics.
Antibody Name:
DALRD3 Antibody (PACO36258)
Antibody SKU:
PACO36258
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human DALR anticodon-binding domain-containing protein 3 protein (182-481AA)
DALR anticodon-binding domain-containing protein 3, DALRD3
UniProt Protein Function:
DALRD3: 4 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 3p21.31Molecular Function: arginine-tRNA ligase activity; ATP bindingBiological Process: arginyl-tRNA aminoacylation
UniProt Protein Details:
NCBI Summary:
The exact function of this gene is not known. It encodes a protein with a DALR anticodon binding domain similar to that of class Ia aminoacyl tRNA synthetases. This gene is located in a cluster of genes (with a complex sense-anti-sense genome architecture) on chromosome 3, and contains two micro RNA (miRNA) precursors (mir-425 and mir-191) in one of its introns. Preferential expression of this gene (the miRNAs and other genes in the cluster) in testis suggests a role of this gene in spermatogenesis (PMID:19906709). [provided by RefSeq, Feb 2013]
