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DACT3 Monoclonal Antibody [P2A5AT] (CPAB0563)

SKU:
CPAB0563
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
P2A5AT
Applications:
WB
ELISA
IHC
€149
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Description

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DACT3 Monoclonal Antibody [P2A5AT] (CPAB0563)

The DACT3 Polyclonal Antibody (CPAB0563) is a valuable tool for research involving DACT3, a protein that plays a role in cell signaling pathways and is implicated in various biological processes. This antibody, derived from rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the DACT3 protein, researchers can accurately detect and analyze its expression in different cell types, making it ideal for studies in developmental biology and cancer research.

DACT3, also known as Dapper Homolog 3, is involved in regulating Wnt signaling, a crucial pathway for cell growth and differentiation. Its function in these processes makes it a promising target for understanding developmental disorders and tumorigenesis. By studying the role of DACT3, researchers can gain insights into how disruptions in Wnt signaling contribute to diseases like cancer and developmental abnormalities, paving the way for potential therapeutic interventions.

Product Name:DACT3 Antibody
Product Sku:CPAB0563
Size:5μg
Host Species:Mouse
Immunogen:Anti-human DACT3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human DACT3 amino acids 89-22 purified from Ecoli.
Clone:P2A5AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Immunohistochemistry
Purification Method:DACT3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:DACT3 which belongs to the DACT (Dpr/Frodo) gene family plays an imperative role in a negative regulator of Wnt/-catenin signaling. Unlike other Wnt signaling inhibitors that are silenced by DNA methylation, DACT3 repression is linked to bivalent histone modifications.
Synonyms:Dapper homolog 3, Antagonist of beta-catenin Dapper homolog 3, Arginine-rich region 1 protein, DACT3, RRR1, MGC15476.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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