The Dachshund Homolog 1 Polyclonal Antibody (CAB6895) is a valuable tool for researchers studying the Dachshund Homolog 1 protein, a key regulator of cell growth and development. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to Dachshund Homolog 1, it enables researchers to detect and analyze this protein in various cell types, making it an excellent choice for studies in developmental biology and cancer research.Dachshund Homolog 1, also known as DACH1, is a transcription factor that plays a crucial role in controlling gene expression patterns that are essential for proper cell differentiation and tissue development.
Dysregulation of DACH1 has been implicated in various diseases, including cancer and developmental disorders, making it a promising target for therapeutic interventions. By delving into the functions of Dachshund Homolog 1, researchers can gain valuable insights into the molecular pathways underlying these conditions and potentially identify novel treatment strategies.
Product Name:
DACH1 Rabbit Polyclonal Antibody
SKU:
CAB6895
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 450-570 of human DACH1 (NP_542937.2).
This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1602
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of 293F, using DACH1 antibody (CAB6895) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
