The Cytokeratin 7 Rabbit Monoclonal Antibody (CAB4357) is a valuable tool for researchers studying Cytokeratin 7, a protein involved in cell structure and epithelial differentiation. This antibody, generated in rabbits, is highly specific for human samples and is validated for use in various research applications, including immunohistochemistry and Western blotting.Cytokeratin 7 is a member of the cytokeratin family of proteins, which are essential components of the cytoskeleton and play a key role in maintaining cell integrity. It is commonly found in epithelial cells, making it a useful marker for identifying various types of cancers, such as breast, lung, and ovarian cancer.
The Cytokeratin 7 Rabbit Monoclonal Antibody binds specifically to Cytokeratin 7 protein, allowing for precise detection and localization in tissue samples.Understanding the expression and localization of Cytokeratin 7 can provide valuable insights into the biology of cancer cells and may aid in the development of targeted therapies and diagnostic tools. The high specificity and sensitivity of the CAB4357 antibody make it a reliable choice for researchers conducting studies in oncology, pathology, and cell biology.
Product Name:
Cytokeratin 7 (KRT7) Rabbit Monoclonal Antibody
SKU:
CAB4357
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 291-463 of human Cytokeratin 7 (KRT7) (P08729).
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
Purification Method:
Affinity purification
Gene ID:
3855
Clone Number:
ARC0978
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cytokeratin 7 (KRT7) (KRT7) Rabbit mAb (CAB4357) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
