The Cytokeratin 20 Rabbit Monoclonal Antibody (CAB19041) is a highly specific antibody designed for research involving Cytokeratin 20, a protein found in epithelial cells. This antibody, raised in rabbits, is recommended for use in immunohistochemistry and Western blot applications, providing accurate detection and analysis of Cytokeratin 20 protein expression in various tissue samples.Cytokeratin 20 is commonly used as a marker for detecting gastrointestinal adenocarcinomas and other cancers originating from epithelial cells. Its differential expression in various cancer types makes it a valuable tool for cancer research and diagnosis.
The Cytokeratin 20 Rabbit Monoclonal Antibody is ideal for researchers studying the role of Cytokeratin 20 in cancer progression, metastasis, and treatment response.With high specificity and sensitivity, this antibody offers reliable results in immunohistochemistry and Western blotting assays, making it essential for studies focusing on the molecular mechanisms of cancer development and progression. Researchers can trust the Cytokeratin 20 Rabbit Monoclonal Antibody (CAB19041) for accurate and reproducible detection of Cytokeratin 20 protein expression in their research samples.
Product Name:
Cytokeratin 20 (KRT20) Rabbit Monoclonal Antibody
SKU:
CAB19041
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 325-424 of human Cytokeratin 20 (KRT20) (P35900).
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
Purification Method:
Affinity purification
Gene ID:
54474
Clone Number:
ARC0288
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from HT-29 cells, using Cytokeratin 20 (CK20) Rabbit mAb (CAB19041) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
